Molecular-docking study of malaria drug target enzyme transketolase in Plasmodium falciparum 3D7 portends the novel approach to its treatment

Table 1 Different physico-chemical properties of transketolase (Plasmodium falciparum 3D7)

Parameter	Value
Molecular weight	75815.2
Extinction coefficients	82460
Abs 0.1 % (=1 g/l) 1.088, assuming all pairs of Cys residues form cystines	82460
Ext. coefficient	81710
Abs 0.1 % (=1 g/l) 1.078, assuming all Cys residues are reduced	81710
Theoretical pI	6.50
Total number of negatively charged residues (Asp + Glu):	76
Total number of positively charged residues (Arg + Lys):	70
Instability index	38
Grand average of hydropathicity (GRAVY)	-0.402
Aliphatic index	82.89

ISSN: 1751-0473